The Biology of Slowing & Reversing Aging | Dr. David Sinclair | Huberman Lab

This podcast episode delves into the science of aging and offers expert insights into practical strategies for improving longevity and health. It explores the key role of epigenetics and the epigenome in the aging process, emphasizing the importance of gene regulation and the potential for interventions to delay or reverse aging. The episode also discusses the connections between growth, puberty, and lifespan, highlighting the influence of growth hormone and body size on longevity.

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The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Huberman Lab

Aging as a Disease: A Paradigm Shift in Longevity Research

The Epigenome: The Key to Aging and Longevity

The Surprising Link Between Growth, Puberty, and Longevity

Intermittent Fasting: Skip a Meal, Improve Health

The Interplay of Blood Glucose, Sirtuins, and mTOR in Longevity

Resveratrol and Metformin: Longevity Drugs and Their Timing

Resveratrol, Berberine, and Fasting: A Comprehensive Guide

NAD+, NMN, NR and B3 Niacin: Boosting Sirtuins for Healthy Aging

NMN Dosage and Effects: A Comprehensive Guide

Artificial Sweeteners and Longevity: Separating Hype from Science

How to Get Comprehensive Blood Tests and Understand Cholesterol Literature

The Cholesterol Conundrum: Dietary Cholesterol and Serum Cholesterol

Antioxidants: Modulators or Mediators? Understanding the Role of Sirtuins in Aging

Transcription Factors and Gene Therapy: Reversing Aging in Neurons

Obesity and Aging: The Role of NAD and Senescent Cells

Measuring Your Biological Age and the Dangers of X-Rays

The Future of Health: Measuring and Optimizing Your Biological Age

The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Huberman Lab

00:00Aging as a Disease: A Paradigm Shift in Longevity Research

Aging as a Disease: A Paradigm Shift in Longevity Research

07:59The Epigenome: The Key to Aging and Longevity

The Epigenome: The Key to Aging and Longevity

16:21The Surprising Link Between Growth, Puberty, and Longevity

The Surprising Link Between Growth, Puberty, and Longevity

25:27Intermittent Fasting: Skip a Meal, Improve Health

Intermittent Fasting: Skip a Meal, Improve Health

33:05The Interplay of Blood Glucose, Sirtuins, and mTOR in Longevity

The Interplay of Blood Glucose, Sirtuins, and mTOR in Longevity

40:19Resveratrol and Metformin: Longevity Drugs and Their Timing

Resveratrol and Metformin: Longevity Drugs and Their Timing

47:23Resveratrol, Berberine, and Fasting: A Comprehensive Guide

Resveratrol, Berberine, and Fasting: A Comprehensive Guide

54:27NAD+, NMN, NR and B3 Niacin: Boosting Sirtuins for Healthy Aging

NAD+, NMN, NR and B3 Niacin: Boosting Sirtuins for Healthy Aging

1:00:09NMN Dosage and Effects: A Comprehensive Guide

NMN Dosage and Effects: A Comprehensive Guide

1:05:55Artificial Sweeteners and Longevity: Separating Hype from Science

Artificial Sweeteners and Longevity: Separating Hype from Science

1:14:10How to Get Comprehensive Blood Tests and Understand Cholesterol Literature

How to Get Comprehensive Blood Tests and Understand Cholesterol Literature

1:19:56The Cholesterol Conundrum: Dietary Cholesterol and Serum Cholesterol

The Cholesterol Conundrum: Dietary Cholesterol and Serum Cholesterol

1:28:23Antioxidants: Modulators or Mediators? Understanding the Role of Sirtuins in Aging

Antioxidants: Modulators or Mediators? Understanding the Role of Sirtuins in Aging

1:37:30Transcription Factors and Gene Therapy: Reversing Aging in Neurons

Transcription Factors and Gene Therapy: Reversing Aging in Neurons

1:44:28Obesity and Aging: The Role of NAD and Senescent Cells

Obesity and Aging: The Role of NAD and Senescent Cells

1:52:06Measuring Your Biological Age and the Dangers of X-Rays

Measuring Your Biological Age and the Dangers of X-Rays

1:59:28The Future of Health: Measuring and Optimizing Your Biological Age

The Future of Health: Measuring and Optimizing Your Biological Age