04 Feb 2026
41m

Why America’s Health Crisis Is an Incentive Problem

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The a16z Show

The American health crisis is explored through the lens of environmental factors rather than solely as a healthcare issue. Justin Mares, TrueMed founder and CEO, argues that the U.S. food system, particularly since the 1970s, has become uniquely poisonous due to subsidized crops like corn and soy, leading to the prevalence of ultra-processed foods and chronic diseases. He advocates for reforming crop subsidy systems and incentivizing lifestyle interventions within the healthcare system, drawing parallels to the Amish community's healthier lifestyle. Mares also touches on the potential of GLP-1s and peptides as disruptive technologies, while emphasizing the need to address the root causes of poor health through environmental and dietary changes. TrueMed aims to financially incentivize preventive care.

Outlines

Part 1: The Crisis, Context

Part 2: Policy, Subsidies, Healthcare Failures

Part 3: TrueMed, Incentives, Environment

Part 4: Corporate Influence, Mental Health

Part 5: Future Outlook, Biohacking

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