01 Dec 2025

Episode 216: BRUE (Brief Resolved Unexplained Event)

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Core EM - Emergency Medicine Podcast

This podcast episode of Core EM, co-hosted by Ellen Duncan and Dr. Noumi Chowdhury, discusses Brief Resolved Unexplained Events (BRUE) in pediatric emergency medicine. They define BRUE as a brief, resolved, and unexplained event affecting infants under one year, characterized by cyanosis/pallor, irregular breathing, altered responsiveness, or changes in muscle tone. The hosts differentiate between low-risk and high-risk BRUE, outlining criteria for each and the appropriate diagnostic workup, including the "Misfits" mnemonic for high-risk patients. They emphasize that BRUE is a diagnosis of exclusion and not synonymous with SIDS, highlighting the importance of systematic investigation, judicious testing, and clear return precautions for parents.

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