27 Oct 2025
1h 25m

Longevity 101: a foundational guide to Peter's frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more (re-broadcast)

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The Peter Attia Drive

In this special episode of The Drive, Peter Attia answers foundational questions about longevity, aiming to provide a starting point for newcomers and a refresher for regular listeners. He defines longevity as a function of lifespan and healthspan, emphasizing the importance of both physical, cognitive, and emotional well-being. Attia discusses Medicine 1.0, 2.0, and introduces Medicine 3.0, which focuses on preventing chronic diseases and equally prioritizing healthspan and lifespan. He details the "four horsemen of death" (atherosclerotic diseases, cancer, neurodegenerative diseases, and metabolic diseases), including prevention strategies. He also outlines five key tactics for improving longevity: exercise (using the "centenarian decathlon" framework), nutrition (emphasizing energy balance and protein intake), sleep, drugs and supplements, and emotional health, offering advice for those overwhelmed on where to begin.

Outlines

Part 1: Introduction to Longevity

Part 2: Prevention Strategies

Part 3: Tactics for Longevity

Part 4: Conclusion

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