IBCC Episode 115 - Invasive Candidiasis

In this episode of The Internet Book of Critical Care Podcast, Josh and Adam discuss invasive candidiasis in the ICU, differentiating between colonization and true infection. They classify invasive candidiasis into candidemia without deep-seated involvement, deep-seated involvement without candidemia, and a combination of both. They explore risk factors, diagnostic approaches like blood cultures and beta-D-glucan, and the importance of hardware removal. The hosts discuss treatment strategies, including the use of echinocandins and de-escalation considerations, as well as specific organ systems affected, such as intra-abdominal infections, lungs, and urinary tract. They emphasize prompt treatment of candidemia while cautioning against unnecessary intervention for colonization.