23 Jul 2025
1h 41m

How to Catch Alzheimer’s Before It Starts, with Dr. Eric Topol

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The Dr. Hyman Show

In this episode of The Dr. Hyman Show, Dr. Mark Hyman interviews Dr. Eric Topol about the science of aging and how to prevent age-related diseases. They discuss Dr. Topol's "Welderly Study," which examined people in their 90s and 100s who never had chronic illnesses, revealing that genetics play a smaller role in longevity than previously thought. The conversation covers the importance of lifestyle factors like diet, exercise, sleep, and mental health, as well as the impact of environmental toxins. They explore new technologies for early disease detection, including proteomic clocks, AI-driven analysis of retinal scans and standard blood tests, and liquid biopsies for cancer. The discussion emphasizes proactive and personalized medicine to extend healthspan and prevent heart disease, Alzheimer's, and cancer.

Outlines

Part 1: Introduction and Background

Part 2: Early Detection and Lifestyle Interventions

Part 3: Heart Disease Prevention and AI

Part 4: Cancer Prevention and Future Outlook

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